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Glutamate levels in the brain may be linked to alcohol craving
Craving consists of cognitive, emotional, and behavioral elements related to a desire to drink alcohol, and can be experienced during intoxication, withdrawal, and/or prior to relapse. Different types of craving are hypothesized to be associated with different neurotransmitter systems. For example, reward craving may be mediated by dopamine and opioids, obsessive craving by serotonin, and relief craving by glutamate. This study used magnetic resonance spectroscopy (1H-MRS) to examine the correlation between craving and glutamate levels in the left dorsolateral prefrontal cortex (LDLPFC) of patients with alcohol use disorders (AUDs).

Fourteen participants (8 females, 6 males) underwent 1H-MRS to measure glutamate levels in the LDLPFC. Researchers also used the Pennsylvania Alcohol Craving Scale (PACS) and a research-validated interview method to quantify craving for alcohol and drinking patterns, respectively.
Although the study sample is small, these data suggest that glutamate levels in the LDLPFC are associated with alcohol-craving intensity in patients with AUDs. Glutamate spectroscopy may be able to help identify biological measures of alcohol-craving intensity and help with treatment interventions.
- Mark A. Frye, David J. Hinton, Victor M. Karpyak, Joanna M. Biernacka, Lee J. Gunderson, Jennifer Geske, Scott E. Feeder, Doo-Sup Choi, John D. Port. Elevated Glutamate Levels in the Left Dorsolateral Prefrontal Cortex Are Associated with Higher Cravings for Alcohol. Alcoholism: Clinical and Experimental Research, 2016; DOI: 10.1111/acer.13131
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Yoga can help girls who suffered childhood trauma
As a Creative Arts Therapist who specializes in the body and is a former Yoga teacher this article is not at all surprising. Most therapists who have worked with trauma survivors know that people have a tendency to have some level of dissociation with their bodies. Yoga can gently bring a new level of conscious feeling, movement and functionally of the body which can’t be processed with other modalities.
As a teenager, Rocsana Enriquez ran away from home frequently to escape fights with her mother and sexual abuse from her stepfather. She got involved with street gangs and cycled in and out of juvenile detention.
While she was incarcerated in Central California, she started to learn yoga. It became an outlet for her anger and an antidote to the deep insecurity she felt. Before she got into a fight, she reminded herself to take a deep breath. And she loved the way she felt when she stretched into “Warrior II” pose. “It made me feel very strong,” she said.
A new report by the Center on Poverty and Inequality at Georgetown Law School shows that yoga programs can be particularly effective at helping girls who are incarcerated cope with the effects of trauma that many have experienced. Research shows yoga and mindfulness can promote healthier relationships, increase concentration, and improve self esteem and physical health.
Such programs, if offered more broadly, would be a cost-effective way to help one of the country’s most vulnerable groups heal and improve their lives, the report says.
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