Strong placebo response thwarts painkiller trials

Interesting article, placebo’s as effective as meds.

Drug companies have a problem: they are finding it ever harder to get painkillers through clinical trials. But this isn’t necessarily because the drugs are getting worse. An extensive analysis of trial data¹ has found that responses to sham treatments have become stronger over time, making it harder to prove a drug’s advantage over placebo.

The change in response to placebo treatments for pain, discovered by researchers in Canada, holds true only for US clinical trials. “We were absolutely floored when we found out,” says Jeffrey Mogil, who directs the pain-genetics lab at McGill University in Montreal and led the analysis. Simply being in a US trial and receiving sham treatment now seems to relieve pain almost as effectively as many promising new drugs. Mogil thinks that as US trials get longer, larger and more expensive, they may be enhancing participants’ expectations of their effectiveness.

See the entire article here: http://www.nature.com/news/strong-placebo-response-thwarts-painkiller-trials-1.18511?%3Fftcamp=crm%2Femail%2F%2Fnbe%2FFirstFTEurope%2Fproduct

About RichardB

I am trained and work as a Creative Arts Therapist specializing in group therapy. I have passionately studied, worked, and taught as a hands-on practitioner of the Creative/Expressive and Healing Arts since 1983 integrating various modalities working in a variety of clinical and non-clinical settings. I currently provide Creative Arts and Counseling services to nonprofit agencies as well as occasionally teaching classes and workshops in communities of faith. I use compassion and acceptance to create an environment that is safe and nurturing for all individuals and groups. In my spare time I engage in research and write articles on a variety of subjects, create: poems, music, abstract artwork, and photograph nature.

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